Helicase breaks hydrogen bonds between the complementary strands of the parent DNA molecule

Count 1

Hands together move straight out from body.  Represents the replication fork and the action of helicase creating two single strands at the replication fork..

Single stranded binding proteins prevent the parent DNA molecules from reconnecting

Counts 2 and 3

Arms move towards each other and away from each other two times. Represents the DNA strands "wanting" to reconnect, but not being able to.

Primase adds an RNA primer onto the leading strand

Count 4

Right hand with 5 fingers out moves to left shoulder.  The right hand represents primase placing the primer.

DNA polymerase III builds off the primer and moves in the same direction as helicase, towards the replication fork, building a complementary DNA strand.  It begins at the 5' end of the new daughter DNA strand and moves in the 3' direction

Counts 5 and 6

Right hand on left shoulder starts with 5 fingers out (from the previous step).  This represents the 5' end of the daughter strand.  Then the hand flips to two fingers out and then to 3 fingers out.  The fingers change from 5 to 2 to 3 representing DNA polymerase III moving from the 5' to the 3' end of the daughter strand. (Get it?  FINGERS:  5:2:3, DNA POLYMERASE 5' to 3')

DNA polymerase III moves in a continues motion down the leading strand of the DNA template.

Counts 7 and 8

The right hand with 3 fingers moves along the left hand towards the wrist.  At the end of the motion, your two hands should be next to each other.  The left hand has 5 fingers exposed (representing the 5' end of the parent DNA strand) and the right hand has 3 fingers exposed (representing the 3' end of the daughter DNA strand).  Look!  Your hands are antiparallel!

Now we'll replicate the lagging strand.  Again, the primase adds an RNA primer.

Count 1

The left hand with five fingers moves towards the elbow of the right arm. 

DNA polymerase III also works in a 5' to 3' direction on the growing strand.

Counts 2 and 3

The left hand on the right elbow still has 5 fingers out (the previous step).  This represents the 5' end of the daughter strand.  Then the hand flips to two fingers out and then to 3 fingers out.  The fingers change from 5 to 2 to 3 representing DNA polymerase III moving from the 5' to the 3' end of the daughter strand.

DNA polymerase III adds complementary DNA nucleotides to the lagging strand working away from the replication fork creating a short Okazaki fragment.

Count 4

The left hand, still with three fingers out, moves towards the right shoulder (in the opposite direction as the replication fork was opening). 

To create another Okazaki fragment, again the primase adds an RNA primer.

Count 5

The left hand with five fingers moves towards the wrist of the right arm. 

DNA polymerase III also works in a 5' to 3' direction on the growing strand.

Counts 6 and 7

The left hand on the right elbow still has 5 fingers out (the previous step).  This represents the 5' end of the daughter strand.  Then the hand flips to two fingers out and then to 3 fingers out.  The fingers change from 5 to 2 to 3 representing DNA polymerase III moving from the 5' to the 3' end of the daughter strand.

DNA polymerase III adds complementary DNA nucleotides to the lagging strand working away from the replication fork, creating a second short Okazaki fragment.

Count 8

The left hand with five fingers moves towards the elbow of the right arm. 

DNA polymerase 1 removes the RNA primers from the leading strand (only 1).

Counts 1 and 2

Fingers on right hand double "brush off" the left shoulder (the spot where the primer was added)

DNA polymerase 1 removes the RNA primers from the lagging strand (multiple, one for each Okazaki fragment).

Counts 3, 4, 5 and 6

Fingers on left hand double "brush off" the right elbow and then the right wrist (the spots where the primer was added).

Ligase seals up the breaks in the sugar phosphate backbone between the Okazaki fragments.

Counts 7 and 8

Left hand circles the right wrist, as if "taping" the wrist with a sports tape wrap.

Enzymes double check to make sure the replication preceded properly with little mutation.

Counts 1-8

As if holding a book up to the nose and reading across the page, move your head from left to right between hands held in front of your face.  Imagine you are "proofreading."  There are 8 counts to fill, so feel free to add some personal flare!