IBBiology @Skyline High School

                                                                                                                                                                     

 

Protein Synthesis Unit Plan (10 days)

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Assessment Statements:

Transcription

3.5.1

Compare the structure of RNA and DNA.

 

3.5.2

Outline DNA transcription in terms of the formation of an RNA strand complementary to the DNA strand by RNA polymerase.

 

7.3.1

State that transcription is carried out in a 5' to 3' direction.

 

7.3.2

Distinguish between the sense and antisense strands of DNA.

 

7.3.3

Explain the process of transcription in prokaryotes, including the role of the promoter region, RNA polymerase, nucleoside triphosphates and the terminator.

 

 

RNA Processing

7.1.5

State that eukaryotic genes can contain exons and introns.

 

7.3.4

State that eukaryotic RNA needs the removal of introns to form mature mRNA.

 

 

Translation

3.5.3

Describe the genetic code in terms of codons composed of triplets of bases.

 

3.5.4

Explain the process of translation, leading to polypeptide formation.

 

3.5.5

Discuss the relationship between one gene and one polypeptide.

 

7.4.1

Explain that each tRNA molecule is recognized by a tRNA-activating enzyme that binds a specific amino acid to the tRNA, using ATP for energy.

 

7.4.2

Outline the structure of ribosomes, including protein and RNA composition, large and small subunits, three tRNA binding sites and mRNA binding sites.

 

7.4.3

State that translation consists of initiation, elongation, translocation and termination.

 

7.4.4

State that translation occurs in a 5' to 3' direction.

 

7.4.6

Explain the process of translation, including ribosomes, polysomes, start codons and stop codons.

 

7.4.7

State that free ribosomes synthesize proteins for use primarily within the cell, and that bound ribosomes synthesize proteins primarily for secretion or for lysosomes.

 

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What You Need to Know

 

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Unit Activities List:  

Overview of protein synthesis (doc)

Transcription directed reading (doc)

Transcription animations (1, 2 and 3)

Transcription notes (doc)

Overview and transcription presentations (ppt)

RNA vs. DNA notes

RNA worksheet (pdf)

RNA processing reading (doc)

RNA processing notes (doc)

Alternative Genome reading (pdf)

The genetic code notes (doc)

Breaking the code worksheet

Nitty gritty of translation notes (doc)

Protein synthesis review worksheet packet

Protein synthesis models (doc)

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Key Terms:

 

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Helpful Links:

Transcription

Animation of Transcription

 

RNA processing

mRNA Splicing

 

Translation

Translation

Protein Biosynthesis

Virtual Cell's Educational Animations

DNA Workshop

Transcribe and Translate a Gene

Protein Synthesis

PolyRibsomes

Why do firflies glo?

Animation of Translation

Life Cycle of mRNA

Transcription Game

Protein Synthesis

 

Control of gene expression

RNAi Animation

RNAi Mechanism Animation

RNAinterference with Gene Expression 

RNAi Explained

How Tiny Machines Switch On Genes/Silence Of The Gene

Control of Gene Expression

 

"When we tug at a simple thing in nature, we find it attached to the rest of the world."  John Muir