7.5.2

Outline the difference between fibrous and globular proteins, with reference to two examples of each protein type.

7.5.4

State four functions of proteins, giving a named example of each.

7.4.5

Draw and label a diagram showing the structure of a peptide bond between two amino acids.

3.2.2

Identify amino acids ... from diagrams showing their structure.

3.2.5

Outline the role of condensation and hydrolysis in the relationships between … amino acids and polypeptides

7.5.1

Explain the four levels of protein structure, indicating the significance of each level.

7.5.3

Explain the significance of polar and non-polar amino acids.

3.6.4

Define denaturation.

Protein Structure

• Draw the generalized amino acid structure, identifying the amino group, the carboxyl group, the radical group, and the alpha carbon.

• Define what is meant by “essential amino acid.”

• Explain how the characteristics of R groups (polar, non-polar, and ionic) affect their behavior in protein folding.

• Describe polypeptide chain formation in terms of the formation of peptide bonds and condensation reactions.

• Determine the number of peptide bonds given the number of amino acids in a polypeptide.

• Describe the primary structure of a protein, including the type of bonding involved.

• Describe the secondary structure of a protein, including the type of bonding involved.

• Describe the tertiary structure of a protein, including the types of bonding involved.

• Describe the quaternary structure of a protein.

• Explain the role of chaperones in protein folding.

• Contrast the structure of globular proteins with the structure of fibrous proteins.

• Define denaturation and list conditions that can cause it to happen.

Protein Function

• Define proteomics.

• Contrast the generalized function of globular proteins with generalized function of fibrous proteins.

• List and describe examples of fibrous proteins used in structure and support.

• List and describe examples of fibrous proteins used for movement and contraction.

• List and describe examples of globular proteins used for storage.

• List and describe examples of globular proteins used for transport.

• List and describe examples of globular proteins used as hormones.

• List and describe examples of globular proteins used as receptors.

• List and describe examples of globular proteins used in defense against disease.

• List and describe examples of globular proteins used as enzymes.

• Explain the role of mis-folded proteins in disease (specifically Alzheimer’s).