Statements & Objectives:
8.1.U1 Metabolic pathways consist of chains and cycles of enzyme-catalyzed reactions.
8.1.U2 Enzymes lower the activation energy of the chemical reactions that they catalyze.
8.1.U3 Enzyme inhibitors can be competitive or non-competitive.
8.1.U4 Metabolic pathways can be controlled by end-product inhibition.
8.1.A1 End-product inhibition of the pathway that converts threonine is isoleucine.
8.1.A2 Use of databases to identify potential new anti-malarial drugs.
8.1.S1 Distinguish different types of inhibition from graphs at specified substrate concentration.
8.1.S2 Calculating and plotting rates of reaction from raw experimental results.
8.1.NOS Developments in scientific research follow improvements in computing- developments in bioinformatics, such as the interrogation of databases have facilitated research into metabolic pathways.
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